Rev Med UAS
Rev Med UAS; Vol. 14 No. 3. Julio-Septiembre 2024
ISSN 2007-8013

Adenocarcinoma de páncreas con recidiva a hombro. Reporte de caso

Pancreatic adenocarcinoma with shoulder recurrence. Case report

Alex Fernando Reyes-Acuña1, Hadassa Yuef Martínez-Padrón2, Eleazar Torres-Lozano1, Edgar Iván Pérez-Rodríguez1, Diana Sofia González-Ontiveros1.

  1. Unidad de Radiología e Imagen del Hospital Regional de Alta especialidad de Cd. Victoria “Bicentenario 2010”.
  2. Subdirección de Enseñanza e Investigación del Hospital Regional de Alta Especialidad de Cd. Victoria “Bicentenario 2010”.

*Autor de correspondencia:Hadassa Yuef Martínez-Padrón
Hospital Regional de Alta Especialidad de Ciudad Victoria “Bicentenario 2010”.
Tamaulipas, Cd. Victoria, México. Libramiento Guadalupe Victoria S/N,
Área de Pajaritos, Ciudad Victoria. 8341610224, hadassayufo@gmail.com

DOI http://dx.doi.org/10.28960/revmeduas.2007-8013.v14.n3.005

Texto Completo PDF

Recibido 27 de abril 2024, aceptado 18 de junio 2024

RESUMEN
Objetivo: Reportar un caso de adenocarcinoma de páncreas metastásico a tejidos blandos y hueso de hombro derecho. Material y método: Estudio retrospectivo de femenina de la sexta década de la vida, referido a nuestra unidad para toma de resonancia magnética en fase simple por tumoración en hombro derecho en estudio. Resultados: Se identificó tumoración sólida dependiente de músculo trapecio con extensión a vientre anterior y medio del deltoides e invasión ósea a tercio distal de la clavícula. Conclusiones: Aunque sean poco comunes, las metástasis a músculo son un diagnóstico diferencial importante ante el médico radiólogo para el correcto diagnóstico de los tumores de tejidos blandos.
Palabras clave: Adenocarcinoma, pancreas, hombro, resonancia magnética, metástasis.

ABSTRACT
Objective: Report a case of pancreatic adenocarcinoma metastatic to soft tissues and bone of the right shoulder. Material and method: Retrospective study of a female in the sixth decade of life, referred to our unit for simple phase MRI due to a tumor in the right shoulder under study. Results: A solid tumor was identified dependent on the trapezius muscle with extension to the anterior and medial belly of the deltoid with invasion to the distal third of the clavicle. Conclusions: Although they are rare, muscle metastases are an important differential diagnosis for the radiologist to correctly diagnose soft tissue tumors.
Key words: Adenocarcinoma, pancreas, shoulder, magnetic resonance, metastases.

Referencias

  1. McGuigan A, Kelly P, Turkington RC, Jones C, Coleman HG, McCain RS. Pancreatic cancer: A review of clinical diagnosis, epidemiology, treatment and outcomes. World J Gastroenterol. 2018 Nov 21;24(43):4846-4861. doi: 10.3748/wjg.v24.i43.4846.
  2. Shimizu K, Hashimoto D, Umezaki N, Nakagawa S, Yamamura K, Chikamoto A, et al. Thoracic wall muscle metastasis from pancreatic cancer. Surg Case Rep. 2018 Jan 25;4(1):12. doi: 10.1186/s40792-017-0393-0
  3. Hindosh R, Liaquat H, Brahmbhatt A, Stoll L, Faroun Y, Quiros RM, et al. Rectus abdominis muscle metastasis from pancreatic cancer: a rare entity. Am J Gastroenterol. October 2020 15():p S694. DOI: 10.14309/01.ajg.0000707920.86888.9c
  4. Harmon C, Lamsal S, Harmon T, Khaled M. Travis M. The Path of Most Resistance: A Rare Instance of Metastatic Pancreatic Adenocarcinoma Identified Within Skeletal Muscle. Cureus. March 2021 13(3): e13947. DOI 10.7759/cureus.13947
  5. Chisthi MM, Manju PA. Skeletal muscle metastases from pancreatic carcinoma-a case report and review of literature. Indian J Surg. 2013 Jun;75(3):181-4. doi: 10.1007/s12262-012-0650-1
  6. Shimizu K, Hashimoto D, Umezaki N, Nakagawa S, Yamamura K, Chikamoto A, et al. Thoracic wall muscle metastasis from pancreatic cancer. Surg Case Rep. 2018 Jan 25;4(1):12. doi: 10.1186/s40792-017-0393-0.
  7. Ong N, George M, Dutta R, Ng CH. CT imaging features of skeletal muscle metastasis. Clin Radiol. 2019 May;74(5):374-377. doi: 10.1016/j.crad.2018.12.017.
  8. Peixoto RD, Speers C, McGahan CE, Renouf DJ, Schaeffer DF, Kennecke HF. Prognostic factors and sites of metastasis in unresectable locally advanced pancreatic cancer. Cancer Med. 2015 Aug;4(8):1171-7. doi: 10.1002/cam4.459.
  9. Wolpin BM, Chan AT, Hartge P, Chanock SJ, Kraft P, Hunter DJ, et al. ABO blood group and the risk of pancreatic cancer. J Natl Cancer Inst. 2009 Mar 18;101(6):424-31. doi: 10.1093/jnci/djp020.
  10. Agaram NP. Evolving classification of rhabdomyosarcoma. Histopathology. 2022 Jan;80(1):98-108. doi: 10.1111/his.14449.
  11. Skapek SX, Ferrari A, Gupta AA, Lupo PJ, Butler E, Shipley J, et al. Rhabdomyosarcoma. Nat Rev Dis Primers. 2019 Jan 7;5(1):1. doi: 10.1038/s41572-018-0051-2.
  12. Tsai S, George B, Wittmann D, Ritch P, Krepline A, Aldakkak M, et al. Importance of Normalization of CA19-9 Levels Following Neoadjuvant Therapy in Patients With Localized Pancreatic Cancer. April 2020 271(4):p 740-747. DOI: 10.1097/SLA.0000000000003049
  13. Amundadottir L, Kraft P, Stolzenberg-Solomon RZ, Fuchs CS, Petersen GM, Arslan AA, et al. Genome-wide association study identifies variants in the ABO locus associated with susceptibility to pancreatic cancer. Nat Genet. 2009 Sep;41(9):986-90. doi: 10.1038/ng.429.
  14. Klein A, Brune K, Petersen G, Goggins M, Tersmette A, Offerhaus G, et al. Prospective risk of pancreatic cancer in familial pancreatic cancer kindreds. Cancer Res. 2004;64(7):2634–8. Doi: http://dx.doi.org/10.1158/0008-5472.can-03-3823.
  15. Raimondi S, Maisonneuve P, Lowenfels AB. Epidemiology of pancreatic cancer: an overview. Nat Rev Gastroenterol Hepatol. 2009 Dec;6(12):699-708. doi: 10.1038/nrgastro.2009.177.
  16. Surov A, Hainz M, Holzhausen HJ, Arnold D, Katzer M, Schmidt J, et al. Skeletal muscle metastases: primary tumours, prevalence, and radiological features. Eur Radiol. 2010 Mar;20(3):649-58. doi: 10.1007/s00330-009-1577-1.
  17. Oberoi S, Crane J, Haduong J, Rudzinski E, Wolden S, Dasgupta R, et al. Children’s Oncology Group’s 2023 blueprint for research: Soft tissue sarcomas. Pediatr Blood Cancer. 2023; 70(Suppl. 6):e30556. https://doi.org/10.1002/pbc.30556